Chronic Heart Failure

 

Heart failure does not mean the heart has stopped working. Rather, it means that the heart's pumping power is weaker than normal. With heart failure, blood moves through the heart and body at a slower rate, and pressure in the heart increases. As a result, the heart cannot pump enough oxygen and nutrients to meet the body's needs. The chambers of the heart may respond by stretching to hold more blood to pump through the body or by becoming stiff and thickened.


What Causes Heart Failure?

Heart failure is caused by many conditions that damage the heart muscle, including:

  • Coronary artery disease. Coronary artery disease (CAD), a disease of the arteries that supply blood and oxygen to the heart, causes decreased blood flow to the heart muscle.
  • Heart attack. A heart attack occurs when a coronary artery becomes suddenly blocked, stopping the flow of blood to the heart muscle.
  • Cardiomyopathy. Damage to the heart muscle from causes other than artery or blood flow problems, such as from infections or alcohol or drug abuse.
  • Conditions that overwork the heart. Conditions including high blood pressure, valve disease, thyroid disease, kidney disease, diabetes, or heart defects present at birth can all cause heart failure.

Treating heart failure

In most cases, heart failure is a lifelong condition that cannot be cured. Treatment therefore aims to find a combination of measures, including lifestyle changes, medicines, devices or surgery that will improve heart function or help the body get rid of excess water.

As treatment will usually be lifelong, you and your doctor will need to find a balance of effective treatments that you can manage in the long term so you have the best symptom control and quality of life possible.


How are Mesenchymal Stem Cells (MSC) administered in Stroke?

A typical treatment is as following; stem cells are administered by a license physician.

  • Medical evaluation and blood testing  (Day 1)
  • Hyperbaric chamber (Day 2)
  • 1 intrathecal injection and intravenous injection of Stem Cells (Day 3)

Which Kinds of cells are used in Chronic Heart Failure and how are they obtained?

Adult stem cells are obtained from itc bank from donor tissue or autologous transplant, which is harvested from the patient’s own adipose tissue and it takes 21 days to culture, differentiate and administer the adult stem cells to the patient.



​Rosenstrauch D, Proglajen G, Zidar N, Gregoric ID. Stem cell therapy for ischemic heart failure. Tex Heart 1st J. 2005; 32:339-347.

Rajiv Gulati, MD, PhD; Robert D. Simari, MD. Cell therapy for Acute Myocardial Infarction. Division o Cardiovascular Diseases and Internal Medicine, Mayo Clinic College of Medicine.